Treatment of MCF-10a, MCF-7, and MDA-MD-231 cells with Gallic acid resulted in inhibition in the activity of the exosomal secretory pathway. Gallic acid can decrease the expression of genes involved in exosomes biogenesis (Alix and CD63) and secretion (Rab proteins). In addition, Gallic acid can change the expression of autophagy markers (LC3 and P62) in these cells. MVB: multivesicular body.